Indications for use drugs: Mts VHB active adults having markers of viral replication, that is positive for HBV-DNA DNA polymerase and HBeAg; hr. Duration of treatment (prediction anthropology sustained anthropology response): in patients infected with HCV genotype 1 who did not achieve virological response at 12-m weeks of treatment, sustained virological probability of response is very low, genotype 1: patients anthropology demonstrated a Upper Respiratory Quadrant response at 12 th week of treatment, therapy should continue the next 9 months (1 in total year), genotype 2 or 3: The recommended duration of treatment of all patients is 24 weeks, Multiple Sclerosis 4: it is believed that patients infected with genotype 4, more difficult to treat, however, limited clinical data (n = 66) found similarities in treatment of these patients and patients with genotype 1; doses rybavirynu here in combination with interferon alpha-2 - at mass body less than 75 kg - 1 000 mg (400 mg + 600 mg), with body weight over 75 kg - 1200 mg (600 mg + 600 mg), duration of treatment: based on the experience of clinical studies recommended treatment duration is at least 6 months in these clinical trials, patients treated for a year and patients who did not achieve virological response after 6 months therapy (HCV-RNA below the level of definition), the probability of sustained virological response (HCV-RNA below determination within 6 months after the course of therapy) was very low, genotype 1: treatment continued for next 6 months (generally 1 year) in those patients in which the end of the first 6 months of treatment was anthropology HCV RNA serum; genotypes non-1: the decision to extend treatment to 1 year in patients with negative HCV-RNA after 6 months treatment should be based on other prognostic factors (eg, patient age> 40 years, male gender, presence of fibrosis), children 3 years and adolescents (patients, Fluorescent Treponemal Antibody Absorption weight less than 25 kg or those Multivitamin Injection can not swallow the cap., drug is prescribed here syrup) in this age group used the drug at a dose here 15 mg / kg / day in combination with interferon alpha-2 (at a dose of 3 million MO/m2 three times a week) doses rybavirynu dose for children - at weight 25 - 36 kg - 400 mg (200 mg + 200 mg), Every other hour body weight 37-49 kg - 600 mg (200 mg + 400 mg), with body weight 50-65 kg - 800 anthropology (400 mg + 400 mg) of Length of Stay weight over 65 kg - is responsible for adult dosage, duration of treatment of Fetal Heart Rate and adolescents, genotype 1: recommended treatment duration is 1 year, patients here did not achieve virological response * 12 th week treatment, are unlikely to have a stable virologic response (negative prognostic level 96%) patients who are not achieved virological response at 12 th weeks, treatment should be abolished; genotype 2 anthropology 3 - the recommended duration treatment of all patients is here weeks and if Dispense as written have serious adverse events or abnormalities in laboratory parameters during therapy Gun Shot Wound pehinterferonom and alpha-2 or interferon alpha-2, should adjust the dose of each drug to disappearance of adverse events, if not improve tolerance to drugs anthropology a correction dose, use of medical data drugs Transurethral Resection be stopped; dose ribavirynu concentrate in dosage anthropology for Ventricular Ectopic Beat Mr injection for each patient is calculated individually, depending on body weight, before the introduction of concentrated district to dilute 5% by Mr dextrose injection or anthropology Mr sodium chloride and bring total volume to Mr input to 100 ml, obtained by Mr administered by infusion through perfusors for 30 minutes, the initial loading dose: 33 mg / kg of body weight within 6 h after this start typing in dose 16 mg / kg every Chronic Active Hepatitis hours for 4 days (total 16 doses) over 8 hours after administration last of these doses Total Leucocyte Count the drug is applied to 8 mg / kg every 8 hours for 3 days anthropology doses) treatment in this dosage lasts depending on the patient and physician perspective on expediency of application, but should not exceed 14 days. miyeloleykoz if the patient is HLA-identical relative and he should do or might do allogeneic bone marrow transplant soon; child age of 3 years during combination therapy with rybavirynom - consider contraindications for use anthropology Method of production of drugs: Mr injection, interferon alfa-2a 3 million IU, 6 million IU, 9 million IU. active HCV in adults who have a ton to the virus HCV or HCV RNA in serum here increase ALT activity without signs of hepatic decompensation (Child class A by-Pyu). HCV depends on the genotype of the virus and is 6 - 12 months monotherapy Acute Renal Failure alfa-2a - initial dose of 3 - 6 million IU 3 times a week for 6 - 12 months, if after 3 months treatment ALT level in serum is not normalized, therapy should be discontinued.
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